Source:http://linkedlifedata.com/resource/pubmed/id/12757226
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
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| pubmed:dateCreated |
2003-5-21
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| pubmed:abstractText |
Scrub typhus is an acute febrile illness caused by infection with Orientia tsutsugamushi transmitted by the bite of larval trombiculid mites (chiggers). A prospective study was conducted in septic shock patients in Maharat Hospital, Nakhon Ratchasima Province, Thailand, from 12 November 2001 to 5 January 2002. Of the 51 septic shock patients studied during the 7 week period, 18 (35.3%) were found to have evidence of scrub typhus infection; 3 patients (16.7%) died. In this study, septic shock caused by Orientia tsutsugamushi is the most prominent (35.3%) in endemic area of scrub typhus. Scrub typhus with septic shock patients results in organ failure: respiratory failure, DIC were predominant, followed by renal and hepatic involvement. Two deaths were due to respiratory failure and one death was as a result of combined respiratory and renal failure. Fever was the most common symptom, followed by headache, myalgia and dyspnea; lymphadenophathy and eschar are common signs. Laboratory findings revealed that almost all of the patients had a mild leukocytosis, reduced hematocrit and thrombocytopenia; SGOT, ALP, direct bilirubin (DB), total billirubin (TB), BUN, Cr were elevated; hypoalbuminemia was noted. Urinalysis showed that 88.9% of the patients had albuminuria. 77.8% of patients had abnormal chest X-rays.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Dec
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| pubmed:issn |
0125-1562
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
33
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
780-6
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:12757226-Adult,
pubmed-meshheading:12757226-Aged,
pubmed-meshheading:12757226-Animals,
pubmed-meshheading:12757226-Arachnid Vectors,
pubmed-meshheading:12757226-Aspartate Aminotransferases,
pubmed-meshheading:12757226-Bilirubin,
pubmed-meshheading:12757226-Blood Urea Nitrogen,
pubmed-meshheading:12757226-Creatinine,
pubmed-meshheading:12757226-Disseminated Intravascular Coagulation,
pubmed-meshheading:12757226-Dyspnea,
pubmed-meshheading:12757226-Endemic Diseases,
pubmed-meshheading:12757226-Female,
pubmed-meshheading:12757226-Fever,
pubmed-meshheading:12757226-Headache,
pubmed-meshheading:12757226-Hematocrit,
pubmed-meshheading:12757226-Hospitalization,
pubmed-meshheading:12757226-Humans,
pubmed-meshheading:12757226-Hypoalbuminemia,
pubmed-meshheading:12757226-Leukocytosis,
pubmed-meshheading:12757226-Lymphatic Diseases,
pubmed-meshheading:12757226-Male,
pubmed-meshheading:12757226-Middle Aged,
pubmed-meshheading:12757226-Mites,
pubmed-meshheading:12757226-Multiple Organ Failure,
pubmed-meshheading:12757226-Prospective Studies,
pubmed-meshheading:12757226-Respiratory Insufficiency,
pubmed-meshheading:12757226-Scrub Typhus,
pubmed-meshheading:12757226-Shock, Septic,
pubmed-meshheading:12757226-Thailand,
pubmed-meshheading:12757226-Thrombocytopenia
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| pubmed:year |
2002
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| pubmed:articleTitle |
Septic shock secondary to scrub typhus: characteristics and complications.
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| pubmed:affiliation |
Malaria National Center, Phnom Penh, Cambodia. lonchanthap@yahoo.com
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| pubmed:publicationType |
Journal Article
|