To use combined proton (1H) and sodium 23 (23Na) magnetic resonance (MR) imaging to noninvasively quantify total tissue sodium concentration and to determine if concentration is altered in malignant human brain tumors.
Department of Radiology, Division of MR Research, Johns Hopkins University School of Medicine, 610 N Caroline St, JHOC 4241, Baltimore, MD 21287-0845, USA. rouwerke@mri.jhu.edu