|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007577,
umls-concept:C0016055,
umls-concept:C0021701,
umls-concept:C0033414,
umls-concept:C0035331,
umls-concept:C0044602,
umls-concept:C0086418,
umls-concept:C0109317,
umls-concept:C0225336,
umls-concept:C0486805,
umls-concept:C0752312,
umls-concept:C1150579,
umls-concept:C1333340,
umls-concept:C1366882,
umls-concept:C1370600,
umls-concept:C1514485,
umls-concept:C1705767,
umls-concept:C1705791,
umls-concept:C1879547,
umls-concept:C2936824
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2003-3-26
|
|
pubmed:abstractText |
Extracellular matrix degradation is associated with neovascularization in diabetic retinas. Fibronectin fragments (Fn-fs) are generated during vascular remodeling. The effects of cellular fibronectin (Fn) and selected Fn-fs on adhesion, proliferation, and signal transduction in human retinal endothelial cells (HRECs) were characterized.
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|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0146-0404
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
44
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1704-15
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:12657612-Antibodies, Blocking,
pubmed-meshheading:12657612-Cell Adhesion,
pubmed-meshheading:12657612-Cell Division,
pubmed-meshheading:12657612-Cells, Cultured,
pubmed-meshheading:12657612-Endothelium, Vascular,
pubmed-meshheading:12657612-Enzyme Activation,
pubmed-meshheading:12657612-Enzyme Inhibitors,
pubmed-meshheading:12657612-Fibronectins,
pubmed-meshheading:12657612-Flow Cytometry,
pubmed-meshheading:12657612-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:12657612-Humans,
pubmed-meshheading:12657612-Integrin alpha5beta1,
pubmed-meshheading:12657612-Mitogen-Activated Protein Kinases,
pubmed-meshheading:12657612-Peptide Fragments,
pubmed-meshheading:12657612-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:12657612-Retinal Vessels,
pubmed-meshheading:12657612-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12657612-Signal Transduction
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|
pubmed:year |
2003
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|
pubmed:articleTitle |
Fibronectin fragments promote human retinal endothelial cell adhesion and proliferation and ERK activation through alpha5beta1 integrin and PI 3-kinase.
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|
pubmed:affiliation |
Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida, USA.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
|
