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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-3-12
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pubmed:abstractText |
Monocytes migrate into the glomerular mesangium during acute inflammatory renal disease, differentiate into macrophages, and may play a key role in the development and progression of glomerular scarring. Treatment strategies that inhibit monocyte infiltration ameliorate glomerular injury in animal models. Mesangial matrix contains several potential monocyte-binding domains that may contribute to monocyte entrapment and modulate cell activation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
889-98
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12631069-Cell Adhesion,
pubmed-meshheading:12631069-Cells, Cultured,
pubmed-meshheading:12631069-Cytokines,
pubmed-meshheading:12631069-Extracellular Matrix Proteins,
pubmed-meshheading:12631069-Fibronectins,
pubmed-meshheading:12631069-Glomerular Mesangium,
pubmed-meshheading:12631069-Humans,
pubmed-meshheading:12631069-Interleukin-1,
pubmed-meshheading:12631069-Interleukin-6,
pubmed-meshheading:12631069-Matrix Metalloproteinase 9,
pubmed-meshheading:12631069-Monocytes,
pubmed-meshheading:12631069-Solubility,
pubmed-meshheading:12631069-Tissue Inhibitor of Metalloproteinases,
pubmed-meshheading:12631069-Transforming Growth Factor beta,
pubmed-meshheading:12631069-Tumor Necrosis Factor-alpha
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pubmed:year |
2003
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pubmed:articleTitle |
Monocyte adhesion to mesangial matrix modulates cytokine and metalloproteinase production.
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pubmed:affiliation |
Department of Nephrology, University Hospital Birmingham NHS Trust, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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