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pubmed-article:12593629pubmed:abstractTextA novel postsynaptic antagonist of N-methyl-D-aspartate (NMDA) receptors, CP-101,606-27 may attenuate the effects of focal ischemia. In current experiments, the authors investigated its neuroprotective effect alone and in combination with recombinant tissue plasminogen activator (rt-PA) in thromboembolic focal cerebral ischemia in rats.lld:pubmed
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pubmed-article:12593629pubmed:articleTitleReduced brain infarct volume and improved neurological outcome by inhibition of the NR2B subunit of NMDA receptors by using CP101,606-27 alone and in combination with rt-PA in a thromboembolic stroke model in rats.lld:pubmed
pubmed-article:12593629pubmed:affiliationAcute Stroke Program, Neurology Division, University of Alberta Hospital, Edmonton, Alberta, Canada.lld:pubmed
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