Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-2-11
pubmed:abstractText
We recently demonstrated that the sarcolemmal ATP-sensitive potassium (sarcK(ATP)) channel plays a key role in cardioprotection against ischemia/reperfusion injuries in Kir6.2-knockout (KO) mice. In the present study, we evaluated the effects of diazoxide, a mitochondrial ATP-sensitive potassium (mitoK(ATP)) channel opener, on ischemia-induced myocardial stunning in sarcK(ATP) channel-deficient mice.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1524-4539
pubmed:author
pubmed:issnType
Electronic
pubmed:day
11
pubmed:volume
107
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
682-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12578868-Action Potentials, pubmed-meshheading:12578868-Adenosine Triphosphate, pubmed-meshheading:12578868-Animals, pubmed-meshheading:12578868-Benzamides, pubmed-meshheading:12578868-Cardiotonic Agents, pubmed-meshheading:12578868-Diazoxide, pubmed-meshheading:12578868-Membrane Proteins, pubmed-meshheading:12578868-Mice, pubmed-meshheading:12578868-Mice, Inbred C57BL, pubmed-meshheading:12578868-Mice, Knockout, pubmed-meshheading:12578868-Mitochondria, Heart, pubmed-meshheading:12578868-Myocardial Contraction, pubmed-meshheading:12578868-Myocardial Ischemia, pubmed-meshheading:12578868-Myocardial Reperfusion, pubmed-meshheading:12578868-Myocardial Stunning, pubmed-meshheading:12578868-Potassium Channel Blockers, pubmed-meshheading:12578868-Potassium Channels, pubmed-meshheading:12578868-Potassium Channels, Inwardly Rectifying, pubmed-meshheading:12578868-Recovery of Function, pubmed-meshheading:12578868-Sarcolemma
pubmed:year
2003
pubmed:articleTitle
Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.
pubmed:affiliation
Department of Pharmacology, Graduate School of Medicine, Chiba University, Chiba, Japan.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't