rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-2-11
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pubmed:abstractText |
We recently demonstrated that the sarcolemmal ATP-sensitive potassium (sarcK(ATP)) channel plays a key role in cardioprotection against ischemia/reperfusion injuries in Kir6.2-knockout (KO) mice. In the present study, we evaluated the effects of diazoxide, a mitochondrial ATP-sensitive potassium (mitoK(ATP)) channel opener, on ischemia-induced myocardial stunning in sarcK(ATP) channel-deficient mice.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Benzamides,
http://linkedlifedata.com/resource/pubmed/chemical/Cardiotonic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Diazoxide,
http://linkedlifedata.com/resource/pubmed/chemical/HMR 1098,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channel Blockers,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels, Inwardly...,
http://linkedlifedata.com/resource/pubmed/chemical/mitochondrial K(ATP) channel
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
682-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12578868-Action Potentials,
pubmed-meshheading:12578868-Adenosine Triphosphate,
pubmed-meshheading:12578868-Animals,
pubmed-meshheading:12578868-Benzamides,
pubmed-meshheading:12578868-Cardiotonic Agents,
pubmed-meshheading:12578868-Diazoxide,
pubmed-meshheading:12578868-Membrane Proteins,
pubmed-meshheading:12578868-Mice,
pubmed-meshheading:12578868-Mice, Inbred C57BL,
pubmed-meshheading:12578868-Mice, Knockout,
pubmed-meshheading:12578868-Mitochondria, Heart,
pubmed-meshheading:12578868-Myocardial Contraction,
pubmed-meshheading:12578868-Myocardial Ischemia,
pubmed-meshheading:12578868-Myocardial Reperfusion,
pubmed-meshheading:12578868-Myocardial Stunning,
pubmed-meshheading:12578868-Potassium Channel Blockers,
pubmed-meshheading:12578868-Potassium Channels,
pubmed-meshheading:12578868-Potassium Channels, Inwardly Rectifying,
pubmed-meshheading:12578868-Recovery of Function,
pubmed-meshheading:12578868-Sarcolemma
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pubmed:year |
2003
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pubmed:articleTitle |
Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.
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pubmed:affiliation |
Department of Pharmacology, Graduate School of Medicine, Chiba University, Chiba, Japan.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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