Source:http://linkedlifedata.com/resource/pubmed/id/12533949
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2003-1-21
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pubmed:abstractText |
Hepatic hyaluronan is a glycosaminoglycan synthesised in the liver mainly by mesenchymal cells and degraded by liver sinusoidal endothelial cells. Serum hyaluronan was measured, using enzyme-linked binding protein assay (Chugai, Japan) in 30 patients with cirrhosis of different etiologies (alcohol n = 15, primary biliary cirrhosis n = 4, hepatitis B n = 5, hepatitis C n = 6). Hyaluronan levels were significantly higher in patients with liver cirrhosis (398 +/- 375.4 ng/ml) than in the controls (36.5 +/- 26.9 ng/ml). There was no significant difference in hialuronan levels between the different etiologies of the disease. Hyaluronan level increased proportionally to the severity of cirrhosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:author | |
pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
80-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12533949-Adult,
pubmed-meshheading:12533949-Biological Markers,
pubmed-meshheading:12533949-Case-Control Studies,
pubmed-meshheading:12533949-Disease Progression,
pubmed-meshheading:12533949-Female,
pubmed-meshheading:12533949-Humans,
pubmed-meshheading:12533949-Hyaluronic Acid,
pubmed-meshheading:12533949-Liver Cirrhosis,
pubmed-meshheading:12533949-Liver Failure,
pubmed-meshheading:12533949-Liver Function Tests,
pubmed-meshheading:12533949-Male,
pubmed-meshheading:12533949-Middle Aged,
pubmed-meshheading:12533949-Probability,
pubmed-meshheading:12533949-Prognosis,
pubmed-meshheading:12533949-Sensitivity and Specificity,
pubmed-meshheading:12533949-Severity of Illness Index,
pubmed-meshheading:12533949-Statistics, Nonparametric
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pubmed:year |
2002
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pubmed:articleTitle |
Serum hyaluronan as a possible biomarker of liver insufficiency in cirrhotic patients.
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pubmed:affiliation |
Department of Infectious Diseases, Medical Academy of Bia?ystok, Bia?ystok, Poland. oliwa@amb.ac.bialystok.pl
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pubmed:publicationType |
Journal Article,
Comparative Study
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