Linked Life Data

12482822

Source:http://linkedlifedata.com/resource/pubmed/id/12482822

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2002-12-16
pubmed:abstractText
We previously reported that plasminogen activator inhibitor 1 (PAI-1), in the presence of vitronectin (VN), inhibits thrombin activity in vitro. Furthermore, we demonstrated in human atherosclerotic plaques the colocalization of thrombin, PAI-1, and VN, as well as activity of thrombin and PAI-1. Here, we show that PAI-1 is a local thrombin inhibitor in vivo.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1524-4636
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1978-83
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12482822-Animals, pubmed-meshheading:12482822-Carotid Arteries, pubmed-meshheading:12482822-Carotid Stenosis, pubmed-meshheading:12482822-Cell Division, pubmed-meshheading:12482822-Connective Tissue, pubmed-meshheading:12482822-Disease Models, Animal, pubmed-meshheading:12482822-Hirudins, pubmed-meshheading:12482822-Immunohistochemistry, pubmed-meshheading:12482822-Ligation, pubmed-meshheading:12482822-Mice, pubmed-meshheading:12482822-Mice, Inbred C57BL, pubmed-meshheading:12482822-Mice, Knockout, pubmed-meshheading:12482822-Muscle, Smooth, Vascular, pubmed-meshheading:12482822-Plasminogen Activator Inhibitor 1, pubmed-meshheading:12482822-Prothrombin, pubmed-meshheading:12482822-Tunica Intima, pubmed-meshheading:12482822-Tunica Media, pubmed-meshheading:12482822-Vitronectin
pubmed:year
2002
pubmed:articleTitle
Plasminogen activator inhibitor 1 and vitronectin protect against stenosis in a murine carotid artery ligation model.
pubmed:affiliation
Department of Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't