Linked Life Data

12375644

Source:http://linkedlifedata.com/resource/pubmed/id/12375644

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2002-10-11
pubmed:abstractText
We developed a decision-support system, the flow cytometry workstation (FCW), that provides variable panel definitions, age-adjusted reference ranges, and graphic display of immunologic trends. Automated quality assurance functions include validation of flow cytometry data using user-defined monoclonal antibody sums and delta check computations. We evaluated the FCW to determine whether it would reduce CD4+ technical and clerical errors and to discover patterns or trends within flow cytometric data for research purposes. The FCW reduced the number of technical and clerical errors in its first 2 years of use (P = .003). User-defined quality assurance summation checks such as CD2+ + CD20+ = 95% +/- 5% were applied to a 10-year data set as part of a retrospective analysis. The FCW discovered a relationship between specimen processing and the number of results appearing out of range: 58.11% of reported samples appeared out of range in 1993 compared with 2% in 1996 (P1 < .001). The FCW is a foundation for quality improvement and outcomes-based research for clinical flow cytometry and serves as a platform for state-of-the-art laboratory management.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-9173
pubmed:author
pubmed:issnType
Print
pubmed:volume
118
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
567-73
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
A decision-support system for flow cytometry immunophenotyping.
pubmed:affiliation
Department of Pathology and Anatomical Sciences, School of Medicine, University of Missouri-Columbia, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Evaluation Studies