12234285

Source:http://linkedlifedata.com/resource/pubmed/id/12234285

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017262, umls-concept:C0033634, umls-concept:C0185117, umls-concept:C0227651, umls-concept:C0752312, umls-concept:C1314939, umls-concept:C1413791, umls-concept:C2911684
pubmed:issue	4
pubmed:dateCreated	2002-9-17
pubmed:abstractText	The induction of excess matrix in renal fibrosis seems to be mediated, at least in part, by the transforming growth factor-beta (TGF-beta)-mediated induction of connective tissue growth factor (CTGF) in mesangial cells.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AR 45879
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0323470
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Connective Tissue Growth Factor, http://linkedlifedata.com/resource/pubmed/chemical/Ctgf protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Immediate-Early Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides..., http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase C, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Smad Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Sp1 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators, http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	0085-2538
pubmed:author	pubmed-author:AbrahamDavid JDJ, pubmed-author:BlomIngrid EIE, pubmed-author:ChenYoujunY, pubmed-author:GoldschmedingRoelR, pubmed-author:LeaskAndrewA, pubmed-author:SaSusanS
pubmed:issnType	Print
pubmed:volume	62
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1149-59
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:12234285-Animals, pubmed-meshheading:12234285-Cells, Cultured, pubmed-meshheading:12234285-Connective Tissue Growth Factor, pubmed-meshheading:12234285-DNA-Binding Proteins, pubmed-meshheading:12234285-Gene Expression, pubmed-meshheading:12234285-Glomerular Mesangium, pubmed-meshheading:12234285-Immediate-Early Proteins, pubmed-meshheading:12234285-Intercellular Signaling Peptides and Proteins, pubmed-meshheading:12234285-MAP Kinase Signaling System, pubmed-meshheading:12234285-Mitogen-Activated Protein Kinases, pubmed-meshheading:12234285-Phosphorylation, pubmed-meshheading:12234285-Promoter Regions, Genetic, pubmed-meshheading:12234285-Protein Kinase C, pubmed-meshheading:12234285-Protein-Serine-Threonine Kinases, pubmed-meshheading:12234285-Protein-Tyrosine Kinases, pubmed-meshheading:12234285-RNA, Messenger, pubmed-meshheading:12234285-Rats, pubmed-meshheading:12234285-Response Elements, pubmed-meshheading:12234285-Smad Proteins, pubmed-meshheading:12234285-Sp1 Transcription Factor, pubmed-meshheading:12234285-Trans-Activators, pubmed-meshheading:12234285-Transforming Growth Factor beta
pubmed:year	2002
pubmed:articleTitle	CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC.
pubmed:affiliation	FibroGen, Inc., 225 Gateway Boulevard, South San Francisco, CA 94080, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't