rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2002-8-8
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pubmed:abstractText |
The eye lens provides a good model for the study of regulation of cell differentiation, in which lens-specific delta1-crystallin expression serves as an indicator of the differentiated state of the cells. It has been indicated that the SOX2, Pax6 and Maf proteins are the major regulators of lens cell differentiation. To clarify the individual roles of these transcription factors, we analysed their participation in regulation of the delta1-crystallin enhancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Crystallins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Eye Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/HMGB Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PAX6 protein,
http://linkedlifedata.com/resource/pubmed/chemical/Paired Box Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/SOXB1 Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Sox2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1356-9597
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
791-805
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12167158-Animals,
pubmed-meshheading:12167158-Base Sequence,
pubmed-meshheading:12167158-Binding Sites,
pubmed-meshheading:12167158-Cells, Cultured,
pubmed-meshheading:12167158-Crystallins,
pubmed-meshheading:12167158-DNA Primers,
pubmed-meshheading:12167158-DNA-Binding Proteins,
pubmed-meshheading:12167158-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:12167158-Enhancer Elements, Genetic,
pubmed-meshheading:12167158-Eye Proteins,
pubmed-meshheading:12167158-HMGB Proteins,
pubmed-meshheading:12167158-Homeodomain Proteins,
pubmed-meshheading:12167158-Lens, Crystalline,
pubmed-meshheading:12167158-Mice,
pubmed-meshheading:12167158-Mice, Transgenic,
pubmed-meshheading:12167158-Molecular Sequence Data,
pubmed-meshheading:12167158-Nuclear Proteins,
pubmed-meshheading:12167158-Paired Box Transcription Factors,
pubmed-meshheading:12167158-Repressor Proteins,
pubmed-meshheading:12167158-SOXB1 Transcription Factors,
pubmed-meshheading:12167158-Sequence Homology, Nucleic Acid,
pubmed-meshheading:12167158-Transcription Factors
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pubmed:year |
2002
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pubmed:articleTitle |
Distinct roles of SOX2, Pax6 and Maf transcription factors in the regulation of lens-specific delta1-crystallin enhancer.
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pubmed:affiliation |
Laboratory of Developmental Biology, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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