Source:http://linkedlifedata.com/resource/pubmed/id/12088431
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2002-6-28
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pubmed:abstractText |
Eight new polyketide-derived metabolites [cladoacetals A and B (1 and 2), 3-(2-formyl-3-hydroxyphenyl)propionic acid (3), 3-deoxyisoochracinic acid (4), isoochracinol (5), 7-hydroxy-3-(2,3-dihydroxybutyl)-1(3H)-isobenzofuranone (6), (+)-cyclosordariolone (10), and altersolanol J (11)] and six known metabolites [two isomeric 1-(1,3-dihydro-4-hydroxy-1-isobenzofuranyl)butan-2,3-diols (7a/b), 7-hydroxy-1(3H)-isobenzofuranone (8), isoochracinic acid (9), altersolanol A (12), and macrosporin (13)] have been isolated from solid-substrate fermentation cultures of an undetermined fungicolous isolate (NRRL 29097) that resembles Cladosporium sp. All structures were assigned primarily by analysis of 1D and/or 2D NMR data. Five of the compounds showed antibacterial activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
876-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12088431-Anti-Bacterial Agents,
pubmed-meshheading:12088431-Anti-Infective Agents,
pubmed-meshheading:12088431-Aspergillus flavus,
pubmed-meshheading:12088431-Bacillus subtilis,
pubmed-meshheading:12088431-Candida albicans,
pubmed-meshheading:12088431-Fusarium,
pubmed-meshheading:12088431-Hydrolysis,
pubmed-meshheading:12088431-Microbial Sensitivity Tests,
pubmed-meshheading:12088431-Mitosporic Fungi,
pubmed-meshheading:12088431-Molecular Structure,
pubmed-meshheading:12088431-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:12088431-Polycyclic Hydrocarbons, Aromatic,
pubmed-meshheading:12088431-Spectrometry, Mass, Electrospray Ionization,
pubmed-meshheading:12088431-Staphylococcus aureus,
pubmed-meshheading:12088431-Stereoisomerism
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pubmed:year |
2002
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pubmed:articleTitle |
Biologically active polyketide metabolites from an undetermined fungicolous hyphomycete resembling Cladosporium.
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pubmed:affiliation |
Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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