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pubmed:abstractText |
In recent studies performed on cultured cells and experimental nephropathies, it has been hypothesized that tubular epithelial cells (TEC), via epithelial-mesenchymal transformation (EMT), can become collagen-producing cells. According to this theory, they should proceed through several activating steps, such as proliferation and phenotype changes, to eventually synthesize extracellular matrix (ECM).
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pubmed:affiliation |
Renal Research Association, Renal Immunopathology Centre, San Carlo Borromeo Hospital, Via Pio II, 3, 20153 Milan, Italy. mp.rastaldi@oscb.sined.net
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