Linked Life Data

12078192

Source:http://linkedlifedata.com/resource/pubmed/id/12078192

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-6-24
pubmed:abstractText
Biological regulatory mechanism which supports bone cell development within the context of proliferation/differentiation relationship serves as a viable basis for addressing skeletal disorders and provides experiment and theoretic basis for selection and utilization of growth factors to reconstruct bone defect. Osteoblast-like cells isolated from human calvarium were used in this study. IGF-II were investigated by adding in the culture medium with different concentration. The results showed that IGF-II stimulated DNA, collagen synthesis and ALP activity of human osteoblast-like cells. Its effects were strong for proliferation and differentiation of osteoblast cells, when 10 ng/ml of four different concentrations (0.1, 1, 10 and 100 ng/ml) were used. IGF-II was proved to be important factor in bone regeneration.
pubmed:language
chi
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1000-1182
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
69-72
pubmed:dateRevised
2010-4-29
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[The effects of IGF-II on the proliferation and differentiation of human osteoblast-like cells].
pubmed:affiliation
Department of Oral and Maxillofacial Surgery, West China University of Medical Sciences.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't