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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2002-5-29
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pubmed:abstractText |
A quantitative understanding of the intracellular trafficking of plasmids delivered by nonviral vectors is essential for optimizing vector functions to increase their transfection efficiency. In this study, quantitative methods were developed to measure plasmids delivered to the nucleus, and the relationship between transfection activity and the number of plasmids in the nucleus were analyzed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0724-8741
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12033367-Animals,
pubmed-meshheading:12033367-Cations,
pubmed-meshheading:12033367-Cell Nucleus,
pubmed-meshheading:12033367-Dose-Response Relationship, Drug,
pubmed-meshheading:12033367-Drug Delivery Systems,
pubmed-meshheading:12033367-Drug Evaluation, Preclinical,
pubmed-meshheading:12033367-Gene Expression Regulation,
pubmed-meshheading:12033367-Liposomes,
pubmed-meshheading:12033367-Plasmids,
pubmed-meshheading:12033367-Polymerase Chain Reaction,
pubmed-meshheading:12033367-Rats,
pubmed-meshheading:12033367-Transfection,
pubmed-meshheading:12033367-Tumor Cells, Cultured
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pubmed:year |
2002
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|
pubmed:articleTitle |
Quantitative analysis of correlation between number of nuclear plasmids and gene expression activity after transfection with cationic liposomes.
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pubmed:affiliation |
Faculty of Pharmaceutical Sciences, The University of Tokushima, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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