Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1976-3-1
|
pubmed:abstractText |
When female mice were given a dose of 20 X 20 rad X-rays, the specific locus mutation rate among offspring conceived up to 7 weeks after the end of treatment was 1/39887 or 0.18-10(-7)/rad/locus, whereas when the same total dose of 200 rad was given in a single exposure the mutation rate was 9/34813 or 1.85-10(-7)/rad/locus. The lower mutation rate after the 20 X 10 rad dose was obtained whether the total or 200 rad was given over a period of 5 days or 4 weeks, and if only young conceived in the first 20 days, rather than 7 weeks, were considered. It is suggested that each 10 rad fraction had the same small effect, and hence that these results confirm and extend RUSSELL's previous finding that the dose-response relationship for specific locus muations in females is curved.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0027-5107
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
375-82
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:1202329-Animals,
pubmed-meshheading:1202329-Dose-Response Relationship, Radiation,
pubmed-meshheading:1202329-Female,
pubmed-meshheading:1202329-Mice,
pubmed-meshheading:1202329-Mutation,
pubmed-meshheading:1202329-Oocytes,
pubmed-meshheading:1202329-Ovum,
pubmed-meshheading:1202329-Radiation Genetics,
pubmed-meshheading:1202329-X-Rays
|
pubmed:year |
1975
|
pubmed:articleTitle |
Specific locus mutation rates after repeated small radiation doses to mouse oocytes.
|
pubmed:publicationType |
Journal Article
|