Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2002-5-13
pubmed:abstractText
Patients with relapsed or refractory acute myeloid leukemia have a poor prognosis. We tested the safety and efficacy of a diphtheria fusion protein [diphtheria toxin (DT)388 granulocyte-macrophage colony-stimulating factor (GMCSF)] directed against the GMCSF receptor that is strongly expressed by leukemic blasts.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1004-13
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:12006512-Acute Disease, pubmed-meshheading:12006512-Adolescent, pubmed-meshheading:12006512-Adult, pubmed-meshheading:12006512-Aged, pubmed-meshheading:12006512-Aged, 80 and over, pubmed-meshheading:12006512-Alanine Transaminase, pubmed-meshheading:12006512-Aspartate Aminotransferases, pubmed-meshheading:12006512-Bone Marrow Cells, pubmed-meshheading:12006512-Child, pubmed-meshheading:12006512-Cytokines, pubmed-meshheading:12006512-Diphtheria Toxin, pubmed-meshheading:12006512-Female, pubmed-meshheading:12006512-Granulocyte-Macrophage Colony-Stimulating Factor, pubmed-meshheading:12006512-Humans, pubmed-meshheading:12006512-Hypocalcemia, pubmed-meshheading:12006512-Leukemia, Myeloid, pubmed-meshheading:12006512-Liver Failure, pubmed-meshheading:12006512-Male, pubmed-meshheading:12006512-Middle Aged, pubmed-meshheading:12006512-Neoplasm Recurrence, Local, pubmed-meshheading:12006512-Partial Thromboplastin Time, pubmed-meshheading:12006512-Recombinant Fusion Proteins, pubmed-meshheading:12006512-Renal Insufficiency, pubmed-meshheading:12006512-Thymidine, pubmed-meshheading:12006512-Treatment Outcome, pubmed-meshheading:12006512-Tumor Cells, Cultured
pubmed:year
2002
pubmed:articleTitle
Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.
pubmed:affiliation
Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina 27157, USA. afrankel@wfubmc.edu
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Clinical Trial, Phase I