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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-3-20
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pubmed:abstractText |
The cell cycle regulator cyclin D1 plays an important role in parathyroid tumourigenesis. The NciI polymorphism in exon 4 has recently been associated with early onset of hereditary nonpolyposis colorectal cancer and is a prognostic indicator of nonsmall cell lung cancer and squamous cell carcinomas. Furthermore, a limited study of 28 primary hyperparathyroidism (pHPT) patients displayed a tendency of NciI influence on HPT development. We hypothesized that the NciI polymorphism may relate to a risk of developing pHPT.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0954-6820
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
250
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
516-20
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:11902820-Aged,
pubmed-meshheading:11902820-Alleles,
pubmed-meshheading:11902820-Analysis of Variance,
pubmed-meshheading:11902820-Case-Control Studies,
pubmed-meshheading:11902820-Chi-Square Distribution,
pubmed-meshheading:11902820-Cyclin D1,
pubmed-meshheading:11902820-Female,
pubmed-meshheading:11902820-Gene Frequency,
pubmed-meshheading:11902820-Genotype,
pubmed-meshheading:11902820-Humans,
pubmed-meshheading:11902820-Hyperparathyroidism,
pubmed-meshheading:11902820-Male,
pubmed-meshheading:11902820-Middle Aged,
pubmed-meshheading:11902820-Polymerase Chain Reaction,
pubmed-meshheading:11902820-Polymorphism, Genetic
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pubmed:year |
2001
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pubmed:articleTitle |
The NeiI polymorphism in the cyclin D1 gene and sporadic primary hyperparathyroidism.
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pubmed:affiliation |
Department of Surgical Sciences, Uppsala University Hospital, Sweden. pamela.correa@kirurgi.uu.se
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pubmed:publicationType |
Journal Article
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