Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2002-3-12
pubmed:abstractText
Inflammatory mediators such as tumor necrosis factor-alpha (TNF-alpha), interleukin 1beta (IL-1beta), IL-6, and interferon gamma (IFN-gamma) may change coronary plaque integrity by altering vascular smooth muscle cell (VSMC) survival and modifying the extracellular matrix. Insulin-like growth factor-1 (IGF-1) prevents apoptosis, promotes matrix formation, and can decrease TNF-alpha or IL-1beta--induced proteoglycan degradation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Culture Media, Conditioned, http://linkedlifedata.com/resource/pubmed/chemical/DNA, http://linkedlifedata.com/resource/pubmed/chemical/Fas Ligand Protein, http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor Binding..., http://linkedlifedata.com/resource/pubmed/chemical/Insulin-Like Growth Factor I, http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins, http://linkedlifedata.com/resource/pubmed/chemical/Nucleic Acid Synthesis Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, IGF Type 1, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor..., http://linkedlifedata.com/resource/pubmed/chemical/Tnfsf6 protein, rat, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor Decoy..., http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha, http://linkedlifedata.com/resource/pubmed/chemical/recombinant human tumor necrosis...
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1524-4539
pubmed:author
pubmed:issnType
Electronic
pubmed:day
12
pubmed:volume
105
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1220-5
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:11889017-Animals, pubmed-meshheading:11889017-Antibodies, pubmed-meshheading:11889017-Apoptosis, pubmed-meshheading:11889017-Arteriosclerosis, pubmed-meshheading:11889017-Carrier Proteins, pubmed-meshheading:11889017-Cells, Cultured, pubmed-meshheading:11889017-Culture Media, Conditioned, pubmed-meshheading:11889017-DNA, pubmed-meshheading:11889017-Dose-Response Relationship, Drug, pubmed-meshheading:11889017-Fas Ligand Protein, pubmed-meshheading:11889017-Gene Expression, pubmed-meshheading:11889017-Insulin-Like Growth Factor Binding Protein 3, pubmed-meshheading:11889017-Insulin-Like Growth Factor I, pubmed-meshheading:11889017-Interferon-gamma, pubmed-meshheading:11889017-Interleukin-1, pubmed-meshheading:11889017-Interleukin-6, pubmed-meshheading:11889017-Membrane Glycoproteins, pubmed-meshheading:11889017-Muscle, Smooth, Vascular, pubmed-meshheading:11889017-Nucleic Acid Synthesis Inhibitors, pubmed-meshheading:11889017-RNA, Messenger, pubmed-meshheading:11889017-Rats, pubmed-meshheading:11889017-Receptor, IGF Type 1, pubmed-meshheading:11889017-Receptors, Tumor Necrosis Factor, pubmed-meshheading:11889017-Receptors, Tumor Necrosis Factor, Type I, pubmed-meshheading:11889017-Tumor Necrosis Factor Decoy Receptors, pubmed-meshheading:11889017-Tumor Necrosis Factor-alpha
pubmed:year
2002
pubmed:articleTitle
Tumor necrosis factor-alpha regulates insulin-like growth factor-1 and insulin-like growth factor binding protein-3 expression in vascular smooth muscle.
pubmed:affiliation
Division of Cardiology, University Hospital of Geneva, Switzerland.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't