rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2002-3-8
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pubmed:abstractText |
Although recent experimental studies have demonstrated CTLA4Ig to be a potent immunosuppressant in vascularized solid organ allografts, little attention has been given to the effect of this soluble recombinant fusion protein on immunosuppression in composite tissue allografts (CTAs). Using a rat hind limb allograft model, we examined the efficacy of CTLA4Ig against the allograft rejection of composite tissue.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA-4 Antigen,
http://linkedlifedata.com/resource/pubmed/chemical/CTLA4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Ctla4 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoconjugates,
http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/abatacept
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
334-40
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:11884927-Animals,
pubmed-meshheading:11884927-Antigens, CD,
pubmed-meshheading:11884927-Antigens, Differentiation,
pubmed-meshheading:11884927-CTLA-4 Antigen,
pubmed-meshheading:11884927-Graft Rejection,
pubmed-meshheading:11884927-Graft Survival,
pubmed-meshheading:11884927-Graft vs Host Disease,
pubmed-meshheading:11884927-Hindlimb,
pubmed-meshheading:11884927-Immune Tolerance,
pubmed-meshheading:11884927-Immunoconjugates,
pubmed-meshheading:11884927-Immunosuppressive Agents,
pubmed-meshheading:11884927-Male,
pubmed-meshheading:11884927-Rats,
pubmed-meshheading:11884927-Rats, Inbred ACI,
pubmed-meshheading:11884927-Rats, Inbred Lew,
pubmed-meshheading:11884927-T-Lymphocytes,
pubmed-meshheading:11884927-Transplantation, Homologous
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pubmed:year |
2002
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pubmed:articleTitle |
Feasibility of immunosuppression in composite tissue allografts by systemic administration of CTLA4Ig.
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pubmed:affiliation |
Department of Orthopaedic Surgery, Hokkaido University School of Medicine, Hokkaido University, Sapporo 060-8638, Japan. niwasaki@med.hokudai.ac.jp.
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pubmed:publicationType |
Journal Article
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