|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0008902,
umls-concept:C0017262,
umls-concept:C0017638,
umls-concept:C0027651,
umls-concept:C0030190,
umls-concept:C0185117,
umls-concept:C0220901,
umls-concept:C1414313,
umls-concept:C1521991,
umls-concept:C2911684
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2002-2-18
|
|
pubmed:abstractText |
Molecular classification of gliomas is a major challenge in the effort to improve therapeutic decisions. The plasminogen activator system, including plasminogen activator inhibitor type 1 (PAI-1), plays a key role in tumor invasion and neoangiogenesis. Epidermal growth factor receptor (EGFR) is involved in the control of proliferation. The contribution of PAI-1 and EGFR to the survival of gliomas was retrospectively investigated.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0360-3016
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
52
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
592-8
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:11849778-Adolescent,
pubmed-meshheading:11849778-Adult,
pubmed-meshheading:11849778-Aged,
pubmed-meshheading:11849778-Analysis of Variance,
pubmed-meshheading:11849778-Brain Neoplasms,
pubmed-meshheading:11849778-Glioma,
pubmed-meshheading:11849778-Humans,
pubmed-meshheading:11849778-Karnofsky Performance Status,
pubmed-meshheading:11849778-Middle Aged,
pubmed-meshheading:11849778-Neoplasm Proteins,
pubmed-meshheading:11849778-Plasminogen Activator Inhibitor 1,
pubmed-meshheading:11849778-Prognosis,
pubmed-meshheading:11849778-Receptor, Epidermal Growth Factor,
pubmed-meshheading:11849778-Retrospective Studies,
pubmed-meshheading:11849778-Survival Rate
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
PAI-1 and EGFR expression in adult glioma tumors: toward a molecular prognostic classification.
|
|
pubmed:affiliation |
Department of Radiothérapie, CHU, La Timone, France.
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|
pubmed:publicationType |
Journal Article
|
