|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0008059,
umls-concept:C0012133,
umls-concept:C0019682,
umls-concept:C0019699,
umls-concept:C0032105,
umls-concept:C0035668,
umls-concept:C0036043,
umls-concept:C0164662,
umls-concept:C0231221,
umls-concept:C0439242,
umls-concept:C1948062
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|
pubmed:issue |
1
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|
pubmed:dateCreated |
2002-1-30
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|
pubmed:abstractText |
Simple antiretroviral drug combinations might provide a comparable benefit to standard triple regimens in patients with mild HIV disease, because poor adherence and toxicities often compromise the sustained benefit of the latest triple regimens, especially when protease inhibitors are used. Bad adherence is the main cause of virological failure in HIV-positive children. The activity and safety of a double combination of nucleosides with high genetic barrier for resistance (stavudine plus didanosine) was assessed in children with nonadvanced HIV disease.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:issn |
1528-4336
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pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:volume |
3
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
9-16
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11819180-Adolescent,
pubmed-meshheading:11819180-Anti-HIV Agents,
pubmed-meshheading:11819180-CD4-Positive T-Lymphocytes,
pubmed-meshheading:11819180-Child,
pubmed-meshheading:11819180-Child, Preschool,
pubmed-meshheading:11819180-Didanosine,
pubmed-meshheading:11819180-Drug Resistance, Viral,
pubmed-meshheading:11819180-Drug Therapy, Combination,
pubmed-meshheading:11819180-Female,
pubmed-meshheading:11819180-Genotype,
pubmed-meshheading:11819180-HIV Infections,
pubmed-meshheading:11819180-HIV-1,
pubmed-meshheading:11819180-Humans,
pubmed-meshheading:11819180-Male,
pubmed-meshheading:11819180-Mutation,
pubmed-meshheading:11819180-Prospective Studies,
pubmed-meshheading:11819180-RNA, Viral,
pubmed-meshheading:11819180-Spain,
pubmed-meshheading:11819180-Stavudine,
pubmed-meshheading:11819180-Treatment Outcome,
pubmed-meshheading:11819180-Viral Load
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|
pubmed:articleTitle |
Efficacy and safety of stavudine plus didanosine in asymptomatic HIV-infected children with plasma HIV RNA below 50,000 copies per milliliter.
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pubmed:affiliation |
Service of Infectious Diseases, Hospital Carlos III, Instituto de Salud Carlos III, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
