Compound 5 (Cpd 5), a vitamin K analog, inhibits rat hepatocyte DNA synthesis and hepatoma cell growth. The aim of this study was to determine if the inhibitory effect of Cpd 5 on cell growth was related to apoptosis.
Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh School of Medicine, E 1552 Biomedical Science Tower, 200 Lothrop Street, Pittsburgh, PA 15213, USA.