rdf:type |
|
lifeskim:mentions |
umls-concept:C0010453,
umls-concept:C0018284,
umls-concept:C0038250,
umls-concept:C0085112,
umls-concept:C0085243,
umls-concept:C0162371,
umls-concept:C0162867,
umls-concept:C0229601,
umls-concept:C0229671,
umls-concept:C0242767,
umls-concept:C0301944,
umls-concept:C0751781,
umls-concept:C1186763,
umls-concept:C1709630,
umls-concept:C2348480,
umls-concept:C2348609,
umls-concept:C2926735
|
pubmed:issue |
12
|
pubmed:dateCreated |
2002-1-4
|
pubmed:abstractText |
Ex vivo expansion of cord blood (CB) hematopoietic stem and progenitor cells increases cell dose and may reduce the severity and duration of neutropenia and thrombocytopenia after transplantation. This study's purpose was to establish a clinically applicable culture system by investigating the use of cytokines, serum-free media, and autologous plasma for the expansion of CB cells and the engraftment of expanded product in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0041-1132
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
41
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1567-76
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:11778074-Animals,
pubmed-meshheading:11778074-Antigens, CD34,
pubmed-meshheading:11778074-Cell Culture Techniques,
pubmed-meshheading:11778074-Cell Lineage,
pubmed-meshheading:11778074-Culture Media,
pubmed-meshheading:11778074-Fetal Blood,
pubmed-meshheading:11778074-Graft Survival,
pubmed-meshheading:11778074-Growth Substances,
pubmed-meshheading:11778074-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:11778074-Hematopoietic Stem Cells,
pubmed-meshheading:11778074-Humans,
pubmed-meshheading:11778074-Mice,
pubmed-meshheading:11778074-Mice, Inbred NOD,
pubmed-meshheading:11778074-Mice, SCID,
pubmed-meshheading:11778074-Transplantation, Heterologous
|
pubmed:year |
2001
|
pubmed:articleTitle |
Preclinical ex vivo expansion of cord blood hematopoietic stem and progenitor cells: duration of culture; the media, serum supplements, and growth factors used; and engraftment in NOD/SCID mice.
|
pubmed:affiliation |
Department of Paediatrics, Laboratory Animal Services Centre, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|