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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2001-12-10
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pubmed:abstractText |
Early-onset periodontitis (EOP) is considered to have a genetic basis, which has not been clearly defined. The tumor necrosis factor-alpha (TNF-alpha) gene polymorphism as one of the genetic factors may influence the expression of several chronic inflammatory diseases. The aim of the present study was to evaluate whether the polymorphisms in the 5'-flanking region of the TNF-alpha gene are associated with Japanese EOP patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-3492
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1554-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11759867-5' Flanking Region,
pubmed-meshheading:11759867-Adult,
pubmed-meshheading:11759867-Aggressive Periodontitis,
pubmed-meshheading:11759867-Alleles,
pubmed-meshheading:11759867-Base Sequence,
pubmed-meshheading:11759867-Case-Control Studies,
pubmed-meshheading:11759867-Chi-Square Distribution,
pubmed-meshheading:11759867-Female,
pubmed-meshheading:11759867-Gene Expression Regulation,
pubmed-meshheading:11759867-Gene Frequency,
pubmed-meshheading:11759867-Genetic Predisposition to Disease,
pubmed-meshheading:11759867-Genotype,
pubmed-meshheading:11759867-Haplotypes,
pubmed-meshheading:11759867-Humans,
pubmed-meshheading:11759867-Japan,
pubmed-meshheading:11759867-Male,
pubmed-meshheading:11759867-Monte Carlo Method,
pubmed-meshheading:11759867-Oligonucleotide Probes,
pubmed-meshheading:11759867-Polymerase Chain Reaction,
pubmed-meshheading:11759867-Polymorphism, Genetic,
pubmed-meshheading:11759867-Statistics as Topic,
pubmed-meshheading:11759867-Tumor Necrosis Factor-alpha
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pubmed:year |
2001
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pubmed:articleTitle |
Analysis of single nucleotide polymorphisms in the 5'-flanking region of tumor necrosis factor-alpha gene in Japanese patients with early-onset periodontitis.
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pubmed:affiliation |
Department of Periodontology, Faculty of Dentistry, Niigata University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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