|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2001-10-30
|
|
pubmed:abstractText |
Hypertrophic scars (HSc) are a dermal fibroproliferative disorder that leads to considerable morbidity. Preliminary evidence suggests that interferon (IFN) may improve HSc clinically. The aims of this study were (1) to compare the cell density in HSc and in wounds that heal without the development of HSc (normotrophic scars), (2) to examine the presence of myofibroblasts and apoptosis in normotrophic and HSc scars over time, and (3) to determine if the systemic administration of IFN-alpha2b can induce apoptosis.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0039-6060
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
130
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
798-808
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:11685189-Actins,
pubmed-meshheading:11685189-Adult,
pubmed-meshheading:11685189-Aged,
pubmed-meshheading:11685189-Apoptosis,
pubmed-meshheading:11685189-Burns,
pubmed-meshheading:11685189-Cell Count,
pubmed-meshheading:11685189-Cicatrix, Hypertrophic,
pubmed-meshheading:11685189-Female,
pubmed-meshheading:11685189-Humans,
pubmed-meshheading:11685189-In Situ Nick-End Labeling,
pubmed-meshheading:11685189-Interferon-alpha,
pubmed-meshheading:11685189-Male,
pubmed-meshheading:11685189-Middle Aged,
pubmed-meshheading:11685189-Prospective Studies,
pubmed-meshheading:11685189-Recombinant Proteins
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Myofibroblasts and apoptosis in human hypertrophic scars: the effect of interferon-alpha2b.
|
|
pubmed:affiliation |
Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
