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pubmed:abstractText |
Cellulose acetate phthalate (CAP), a pharmaceutical excipient used for enteric film coating of capsules and tablets, was shown to inhibit infection by the human immunodeficiency virus type 1 (HIV-1) and several herpesviruses. CAP formulations inactivated HIV-1, herpesvirus types 1 (HSV-1) and 2 (HSV-2) and the major nonviral sexually transmitted disease (STD) pathogens and were effective in animal models for vaginal infection by HSV-2 and simian immunodeficiency virus.
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pubmed:affiliation |
Biochemical Virology Laboratory, The Lindsley F Kimball Research Institute of the New York Blood Center, New York, NY 10021, USA. arneurath@worldnet.att.net
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