rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2001-9-27
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pubmed:abstractText |
Infliximab is a humanized antibody against tumor necrosis factor alpha (TNF-alpha) that is used in the treatment of Crohn's disease and rheumatoid arthritis. Approximately 147,000 patients throughout the world have received infliximab. Excess TNF-alpha in association with tuberculosis may cause weight loss and night sweats, yet in animal models it has a protective role in the host response to tuberculosis. There is no direct evidence of a protective role of TNF-alpha in patients with tuberculosis.
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pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0028-4793
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
345
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1098-104
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11596589-Adolescent,
pubmed-meshheading:11596589-Adult,
pubmed-meshheading:11596589-Adverse Drug Reaction Reporting Systems,
pubmed-meshheading:11596589-Aged,
pubmed-meshheading:11596589-Aged, 80 and over,
pubmed-meshheading:11596589-Antibodies, Monoclonal,
pubmed-meshheading:11596589-Arthritis, Rheumatoid,
pubmed-meshheading:11596589-Crohn Disease,
pubmed-meshheading:11596589-Female,
pubmed-meshheading:11596589-Humans,
pubmed-meshheading:11596589-Immunosuppressive Agents,
pubmed-meshheading:11596589-Lung,
pubmed-meshheading:11596589-Male,
pubmed-meshheading:11596589-Middle Aged,
pubmed-meshheading:11596589-Recurrence,
pubmed-meshheading:11596589-Tuberculosis,
pubmed-meshheading:11596589-Tumor Necrosis Factor-alpha
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pubmed:year |
2001
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pubmed:articleTitle |
Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent.
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pubmed:affiliation |
Pulmonary Center, Department of Medicine, Boston University School of Medicine, MA 02118, USA. jkeane@lung.bumc.bu.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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