11568073

Source:http://linkedlifedata.com/resource/pubmed/id/11568073

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017337, umls-concept:C0035126, umls-concept:C0040669, umls-concept:C0080309, umls-concept:C0243043, umls-concept:C0521451
pubmed:issue	12 Suppl 1
pubmed:dateCreated	2001-9-24
pubmed:abstractText	Upregulation of heat shock protein 70 (HSP70) is beneficial in cardioprotection against ischemia-reperfusion injury, but the mechanism of action is unclear. We studied the role of HSP70 overexpression through gene therapy on mitochondrial function and ventricular recovery in a protocol that mimics clinical donor heart preservation.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0147763
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/HSP70 Heat-Shock Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Liposomes
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1524-4539
pubmed:author	pubmed-author:AbunasraHH, pubmed-author:AmraniMM, pubmed-author:JayakumarJJ, pubmed-author:KhanMM, pubmed-author:LatifNN, pubmed-author:MurtuzaBB, pubmed-author:SammutI AIA, pubmed-author:SmolenskiR TRT, pubmed-author:SuzukiKK, pubmed-author:YacoubM HMH
pubmed:issnType	Electronic
pubmed:day	18
pubmed:volume	104
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	I303-7
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11568073-Animals, pubmed-meshheading:11568073-Blotting, Western, pubmed-meshheading:11568073-Gene Expression, pubmed-meshheading:11568073-Gene Therapy, pubmed-meshheading:11568073-Genetic Vectors, pubmed-meshheading:11568073-HSP70 Heat-Shock Proteins, pubmed-meshheading:11568073-Heart Transplantation, pubmed-meshheading:11568073-Humans, pubmed-meshheading:11568073-Immunohistochemistry, pubmed-meshheading:11568073-Liposomes, pubmed-meshheading:11568073-Male, pubmed-meshheading:11568073-Mitochondria, Heart, pubmed-meshheading:11568073-Myocardium, pubmed-meshheading:11568073-Organ Preservation, pubmed-meshheading:11568073-Perfusion, pubmed-meshheading:11568073-Rats, pubmed-meshheading:11568073-Rats, Sprague-Dawley, pubmed-meshheading:11568073-Reperfusion Injury, pubmed-meshheading:11568073-Respirovirus, pubmed-meshheading:11568073-Transfection, pubmed-meshheading:11568073-Up-Regulation, pubmed-meshheading:11568073-Ventricular Function
pubmed:year	2001
pubmed:articleTitle	Heat shock protein 70 gene transfection protects mitochondrial and ventricular function against ischemia-reperfusion injury.
pubmed:affiliation	Department of Cardiothoracic Surgery, National Heart and Lung Institute, Imperial College School of Medicine, Royal Brompton and Harefield Hospital, Harefield, Middlesex, UK. jay.jayakumar@harefield.nthames.nhs.uk
pubmed:publicationType	Journal Article, In Vitro, Research Support, Non-U.S. Gov't