|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2001-9-7
|
|
pubmed:abstractText |
Intracranial aneurysm, which underlies the vast majority of subarachnoid hemorrhage incidences, has a multifactorial etiology, and the importance of genetic factors is increasingly recognized. Development and rupture of intracranial aneurysms involve degradation and remodeling of the vascular wall matrix in which the matrix metalloproteinases (MMPs) play an important role. The possible impact of MMP gene polymorphisms on susceptibility to intracranial aneurysms is still controversial, with conflicting data from different reported studies.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1524-4628
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
32
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2198-202
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:11546917-Adult,
pubmed-meshheading:11546917-Aged,
pubmed-meshheading:11546917-Alleles,
pubmed-meshheading:11546917-Cohort Studies,
pubmed-meshheading:11546917-England,
pubmed-meshheading:11546917-European Continental Ancestry Group,
pubmed-meshheading:11546917-Female,
pubmed-meshheading:11546917-Gene Frequency,
pubmed-meshheading:11546917-Genotype,
pubmed-meshheading:11546917-Humans,
pubmed-meshheading:11546917-Male,
pubmed-meshheading:11546917-Matrix Metalloproteinase 1,
pubmed-meshheading:11546917-Matrix Metalloproteinase 12,
pubmed-meshheading:11546917-Matrix Metalloproteinase 3,
pubmed-meshheading:11546917-Matrix Metalloproteinase 9,
pubmed-meshheading:11546917-Matrix Metalloproteinases,
pubmed-meshheading:11546917-Metalloendopeptidases,
pubmed-meshheading:11546917-Microsatellite Repeats,
pubmed-meshheading:11546917-Middle Aged,
pubmed-meshheading:11546917-Polymorphism, Genetic,
pubmed-meshheading:11546917-Promoter Regions, Genetic,
pubmed-meshheading:11546917-Subarachnoid Hemorrhage
|
|
pubmed:year |
2001
|
|
pubmed:articleTitle |
Polymorphisms in matrix metalloproteinase-1, -3, -9, and -12 genes in relation to subarachnoid hemorrhage.
|
|
pubmed:affiliation |
Human Genetics Research Division, Clinical Neurosciences Research Division, University of Southampton, School of Medicine, UK.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
