Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1975-11-8
pubmed:abstractText
After the DNA of newborn female rats had been labelled by repeated injections of [14C]orotate (totalling 36 mu Ci) during the first 3 weeks of life, approximately 1,000,000 dpm were found in the DNA of the liver, lungs, kidneys, gut, brain, heart and spleen of 8-week-old rats. Methyl methanesulphonate (MMS) (80 mg/kg) and di-(2-chloroethyl)methylamine (HN2) (5 mg/kg) injection increased the amount of 14C-labelled DNA pyrimidine nucleosides excreted in the urine to 5000 dpm from 350 dpm before injection. The effect on RNA products was much less marked.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0009-2797
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
407-12
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed-meshheading:1149171-Animals, pubmed-meshheading:1149171-Animals, Newborn, pubmed-meshheading:1149171-Brain, pubmed-meshheading:1149171-Carbon Radioisotopes, pubmed-meshheading:1149171-Chromatography, Affinity, pubmed-meshheading:1149171-DNA, pubmed-meshheading:1149171-Deoxyribonucleosides, pubmed-meshheading:1149171-Female, pubmed-meshheading:1149171-Injections, Subcutaneous, pubmed-meshheading:1149171-Intestines, pubmed-meshheading:1149171-Kidney, pubmed-meshheading:1149171-Liver, pubmed-meshheading:1149171-Lung, pubmed-meshheading:1149171-Mechlorethamine, pubmed-meshheading:1149171-Methyl Methanesulfonate, pubmed-meshheading:1149171-Myocardium, pubmed-meshheading:1149171-Orotic Acid, pubmed-meshheading:1149171-Pyrimidine Nucleosides, pubmed-meshheading:1149171-Rats, pubmed-meshheading:1149171-Spleen
pubmed:year
1975
pubmed:articleTitle
Increased urinary excretion of labelled deoxyribonucleosides in rats with stable pre-labelled DNA treated with methyl methanesulphonate or nitrogen mustard.
pubmed:publicationType
Journal Article