Linked Life Data

11471545

Source:http://linkedlifedata.com/resource/pubmed/id/11471545

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2001-7-26
pubmed:abstractText
The ability to manipulate the development of pancreatic insulin-producing beta cells has implications for the treatment of type 1 diabetes. Previously, we found that laminin-1, a basement membrane trimeric glycoprotein, promotes beta-cell differentiation. We have investigated the mechanism of this effect, using agents that block the receptors for laminin-1, alpha6 integrin, and alpha-dystroglycan (alpha-DG).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1076-1551
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-14
pubmed:dateRevised
2008-11-20
pubmed:meshHeading
pubmed-meshheading:11471545-Animals, pubmed-meshheading:11471545-Antibodies, Monoclonal, pubmed-meshheading:11471545-Antigens, CD, pubmed-meshheading:11471545-Bromodeoxyuridine, pubmed-meshheading:11471545-Cell Differentiation, pubmed-meshheading:11471545-Cell Survival, pubmed-meshheading:11471545-Cytoskeletal Proteins, pubmed-meshheading:11471545-Dose-Response Relationship, Drug, pubmed-meshheading:11471545-Dystroglycans, pubmed-meshheading:11471545-Enzyme Inhibitors, pubmed-meshheading:11471545-Heterozygote, pubmed-meshheading:11471545-Homozygote, pubmed-meshheading:11471545-Integrin alpha6, pubmed-meshheading:11471545-Islets of Langerhans, pubmed-meshheading:11471545-Laminin, pubmed-meshheading:11471545-Membrane Glycoproteins, pubmed-meshheading:11471545-Mice, pubmed-meshheading:11471545-Mice, Knockout, pubmed-meshheading:11471545-Microscopy, Fluorescence, pubmed-meshheading:11471545-Models, Biological, pubmed-meshheading:11471545-Pancreas, pubmed-meshheading:11471545-Rats, pubmed-meshheading:11471545-Signal Transduction, pubmed-meshheading:11471545-Time Factors
pubmed:year
2001
pubmed:articleTitle
Regulation of laminin 1-induced pancreatic beta-cell differentiation by alpha6 integrin and alpha-dystroglycan.
pubmed:affiliation
Autoimmunity and Transplantation Division, Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't