Linked Life Data

11453575

Source:http://linkedlifedata.com/resource/pubmed/id/11453575

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2001-7-16
pubmed:abstractText
Tumor necrosis factor (TNF)-alpha is a potent inducible cytokine with pleiotropic biological effects, now implicated as a mediator of various physiologic and pathophysiologic events including inflammation, cell survival, growth, differentiation and apoptosis. TNF-alpha functions within a complex and tightly regulated cytokine network, activating multiple signal transduction pathways and inducing or suppressing a wide variety of genes, including those encoding for other cytokines, adhesion molecules and the inducible nitric oxide synthase. TNF-alpha has recently been implicated as a transducer of cardiovascular diseases, namely coronary artery disease and congestive heart failure. This review will summarize established and newer findings on this molecule.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1129-471X
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
408-17
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2001
pubmed:articleTitle
Tumor necrosis factor-alpha and cardiovascular diseases.
pubmed:affiliation
Division of Cardiology, "G. d'Annunzio" University, Chieti, Italy.
pubmed:publicationType
Journal Article, Review