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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2001-7-5
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pubmed:abstractText |
Chromium carcinogenicity and mutagenicity are no longer disputed. However, although chromium has various genetic effects that induce cancer, its mechanism of inducing lung cancer in humans is still not fully understood. p53, a tumor suppressor gene, was found to be infrequently mutated in samples of lung cancer in workers with long occupational exposure to chromium, suggesting other cancer-related genes to be targeted in such tumors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0271-3586
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pubmed:author |
pubmed-author:EwisA AAA,
pubmed-author:HashimotoMM,
pubmed-author:KodamaTT,
pubmed-author:KondoKK,
pubmed-author:LeeJJ,
pubmed-author:MondenYY,
pubmed-author:MukaiKK,
pubmed-author:NakahoriYY,
pubmed-author:ShinkaTT,
pubmed-author:TsuyuguchiMM,
pubmed-author:YokoseTT
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pubmed:copyrightInfo |
Copyright 2001 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
92-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11439401-Adult,
pubmed-meshheading:11439401-Aged,
pubmed-meshheading:11439401-Case-Control Studies,
pubmed-meshheading:11439401-Chromates,
pubmed-meshheading:11439401-Gene Expression Regulation,
pubmed-meshheading:11439401-Genes, ras,
pubmed-meshheading:11439401-Humans,
pubmed-meshheading:11439401-Japan,
pubmed-meshheading:11439401-Lung Neoplasms,
pubmed-meshheading:11439401-Male,
pubmed-meshheading:11439401-Middle Aged,
pubmed-meshheading:11439401-Occupational Diseases,
pubmed-meshheading:11439401-Point Mutation,
pubmed-meshheading:11439401-Polymerase Chain Reaction,
pubmed-meshheading:11439401-Polymorphism, Single-Stranded Conformational
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pubmed:year |
2001
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pubmed:articleTitle |
Occupational cancer genetics: infrequent ras oncogenes point mutations in lung cancer samples from chromate workers.
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pubmed:affiliation |
Department of Public Health, School of Medicine, Tokushima University, Tokushima City, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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