|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003483,
umls-concept:C0017262,
umls-concept:C0019878,
umls-concept:C0036536,
umls-concept:C0036537,
umls-concept:C0042373,
umls-concept:C0079633,
umls-concept:C0086418,
umls-concept:C0128897,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0225336,
umls-concept:C2911684
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|
pubmed:issue |
22
|
|
pubmed:dateCreated |
2001-6-6
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|
pubmed:abstractText |
Proinflammatory cytokines play key roles in atherogenesis and disease progression. Because hyperhomocysteinemia is an independent risk factor for cardiovascular disease, we hypothesized that homocysteine could be atherogenic by altering the expression of specific cytokines in vascular endothelial cells.
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pubmed:grant |
|
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pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1524-4539
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
5
|
|
pubmed:volume |
103
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2717-23
|
|
pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11390343-Aorta, Thoracic,
pubmed-meshheading:11390343-Blotting, Northern,
pubmed-meshheading:11390343-Cells, Cultured,
pubmed-meshheading:11390343-Chemokine CCL2,
pubmed-meshheading:11390343-Chemotaxis,
pubmed-meshheading:11390343-Endothelium, Vascular,
pubmed-meshheading:11390343-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:11390343-Gene Expression Regulation,
pubmed-meshheading:11390343-Homocysteine,
pubmed-meshheading:11390343-Humans,
pubmed-meshheading:11390343-Interleukin-8,
pubmed-meshheading:11390343-RNA, Messenger,
pubmed-meshheading:11390343-Sulfur Compounds,
pubmed-meshheading:11390343-Time Factors,
pubmed-meshheading:11390343-U937 Cells,
pubmed-meshheading:11390343-Vascular Diseases
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|
pubmed:year |
2001
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|
pubmed:articleTitle |
Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease.
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|
pubmed:affiliation |
Department of Cell Biology, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
