Source:http://linkedlifedata.com/resource/pubmed/id/11325469
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-4-30
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pubmed:abstractText |
The secretory glycoprotein (Gs) of respiratory syncytial virus (RSV) was enriched and investigated for its effects on T cells specific for RSV and unrelated antigens. Gs exhibited a dose dependent suppression of lymphoproliferative responses in peripheral blood mononuclear cells (PBMCs), specific for mycobacterial lysates or tetanus toxoid. However, Gs did not inhibit live RSV specific T cell responses. These results suggest that Gs may suppress immune response to unrelated antigens, but should not interfere with the overall development of RSV specific immunity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0168-1702
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-54
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:11325469-Adult,
pubmed-meshheading:11325469-Animals,
pubmed-meshheading:11325469-Humans,
pubmed-meshheading:11325469-Lymphocyte Activation,
pubmed-meshheading:11325469-Respiratory Syncytial Viruses,
pubmed-meshheading:11325469-T-Lymphocytes,
pubmed-meshheading:11325469-Tumor Cells, Cultured,
pubmed-meshheading:11325469-Viral Proteins
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pubmed:year |
2001
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pubmed:articleTitle |
Immunoregulatory role of secreted glycoprotein G from respiratory syncytial virus.
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pubmed:affiliation |
Division of Infectious Diseases and Immunology, Saint Louis University, 3635 Vista Avenue, St. Louis, MO 63110, USA. rayr@slu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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