Source:http://linkedlifedata.com/resource/pubmed/id/11227682
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
2001-2-28
|
| pubmed:abstractText |
Twenty-nine patients with necrotizing fasciitis who were treated with 5% mafenide acetate solution (MAS) as an adjunct after grafting were compared with 45 patients treated without MAS. Statistical analysis of differences was obtained through P values by chi2 testing. The MAS+ (M) and MAS- (C) groups were similar in percent skin deficit (M = 7.5%; C = 9.8%), with the extremity being the most common area of infection. Streptococcus was the most common single organism but polymicrobial infections were the most prevalent (M = 48%; C = 58%). Patients with necrotizing fasciitis treated with MAS had fewer debridements per patient (M = 3.7; C = 5.4), fewer closure procedures (average per patient: M = 1.2; C = 1.73) and a higher percent of first-time closures (83 vs 59%; chi2 = 4.26; P = 0.039). There is a trend toward a lower mortality rate (3.4 vs 13%; chi2 = 2.00; P = 0.158). We conclude that MAS is a useful adjunct in necrotizing fasciitis wound care protocols.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0273-8481
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
35-40
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| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:11227682-Administration, Topical,
pubmed-meshheading:11227682-Adult,
pubmed-meshheading:11227682-Aged,
pubmed-meshheading:11227682-Burns,
pubmed-meshheading:11227682-Case-Control Studies,
pubmed-meshheading:11227682-Fasciitis, Necrotizing,
pubmed-meshheading:11227682-Female,
pubmed-meshheading:11227682-Follow-Up Studies,
pubmed-meshheading:11227682-Humans,
pubmed-meshheading:11227682-Injury Severity Score,
pubmed-meshheading:11227682-Mafenide,
pubmed-meshheading:11227682-Male,
pubmed-meshheading:11227682-Middle Aged,
pubmed-meshheading:11227682-Probability,
pubmed-meshheading:11227682-Reference Values,
pubmed-meshheading:11227682-Retrospective Studies,
pubmed-meshheading:11227682-Skin Transplantation,
pubmed-meshheading:11227682-Solutions,
pubmed-meshheading:11227682-Treatment Outcome,
pubmed-meshheading:11227682-Wound Healing
|
| pubmed:articleTitle |
The use of 5% mafenide acetate solution in the postgraft treatment of necrotizing fasciitis.
|
| pubmed:affiliation |
University of Southern California School of Medicine, Los Angeles, USA.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|