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11206468
Source:
http://linkedlifedata.com/resource/pubmed/id/11206468
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rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0020314
,
umls-concept:C0038760
,
umls-concept:C0243077
,
umls-concept:C0623362
pubmed:issue
2
pubmed:dateCreated
2001-2-5
pubmed:abstractText
Heteroaryl and cycloalkyl sulfonamide-hydroxamic acid MMP inhibitors were investigated. Of these, the pyridyl analogue 2 is the most potent and selective inhibitor of MMP-9 and MMP-13 in vitro.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anthranilic Acids
,
http://linkedlifedata.com/resource/pubmed/chemical/Collagenases
,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxamic Acids
,
http://linkedlifedata.com/resource/pubmed/chemical/MMP13 protein, human
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 1
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 13
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9
,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases
,
http://linkedlifedata.com/resource/pubmed/chemical/Protease Inhibitors
,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0960-894X
pubmed:author
pubmed-author:ChandaPP
,
pubmed-author:CosmiSS
,
pubmed-author:CowlingRR
,
pubmed-author:DiJosephJ FJF
,
pubmed-author:EdrisWW
,
pubmed-author:FOXJ NJN
,
pubmed-author:HsiaoC LCL
,
pubmed-author:JiaJJ
,
pubmed-author:KillarL MLM
,
pubmed-author:LevinJ IJI
,
pubmed-author:NelsonF CFC
,
pubmed-author:SharrM AMA
,
pubmed-author:SkotnickiJ SJS
,
pubmed-author:SundBB
,
pubmed-author:WilhelmJJ
,
pubmed-author:ZaskAA
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
239-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11206468-Animals
,
pubmed-meshheading:11206468-Anthranilic Acids
,
pubmed-meshheading:11206468-Collagenases
,
pubmed-meshheading:11206468-Combinatorial Chemistry Techniques
,
pubmed-meshheading:11206468-Humans
,
pubmed-meshheading:11206468-Hydroxamic Acids
,
pubmed-meshheading:11206468-Inhibitory Concentration 50
,
pubmed-meshheading:11206468-Matrix Metalloproteinase 1
,
pubmed-meshheading:11206468-Matrix Metalloproteinase 13
,
pubmed-meshheading:11206468-Matrix Metalloproteinase 9
,
pubmed-meshheading:11206468-Matrix Metalloproteinases
,
pubmed-meshheading:11206468-Protease Inhibitors
,
pubmed-meshheading:11206468-Structure-Activity Relationship
,
pubmed-meshheading:11206468-Sulfonamides
pubmed:year
2001
pubmed:articleTitle
Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases.
pubmed:affiliation
Wyeth-Ayerst Research, Pearl River, NY 10965, USA. levinji@war.wyeth.com
pubmed:publicationType
Journal Article