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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2001-1-26
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pubmed:abstractText |
During Drosophila embryogenesis, the development of the midgut endoderm depends on interactions with the overlying visceral mesoderm. Here we show that the development of the hindgut also depends on cellular interactions, in this case between the inner ectoderm and outer visceral mesoderm. In this section of the gut, the ectoderm is essential for the proper specification and differentiation of the mesoderm, whereas the mesoderm is not required for the normal development of the ectoderm. Wingless and the fibroblast growth factor receptor Heartless act over sequential but interdependent phases of hindgut visceral mesoderm development. Wingless is required to establish the primordium and to enhance Heartless expression. Later, Heartless is required to promote the proper differentiation of the hindgut visceral mesoderm itself.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Drosophila Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fibroblast Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Wnt1 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/heartless protein, Drosophila,
http://linkedlifedata.com/resource/pubmed/chemical/wg protein, Drosophila
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0950-1991
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
233-42
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11124118-Animals,
pubmed-meshheading:11124118-Body Patterning,
pubmed-meshheading:11124118-Digestive System,
pubmed-meshheading:11124118-Drosophila,
pubmed-meshheading:11124118-Drosophila Proteins,
pubmed-meshheading:11124118-Ectoderm,
pubmed-meshheading:11124118-Gene Expression Regulation, Developmental,
pubmed-meshheading:11124118-Genes, Insect,
pubmed-meshheading:11124118-In Situ Hybridization,
pubmed-meshheading:11124118-Mesoderm,
pubmed-meshheading:11124118-Mitogen-Activated Protein Kinases,
pubmed-meshheading:11124118-Muscle, Smooth,
pubmed-meshheading:11124118-Protein-Tyrosine Kinases,
pubmed-meshheading:11124118-Proto-Oncogene Proteins,
pubmed-meshheading:11124118-Receptors, Fibroblast Growth Factor,
pubmed-meshheading:11124118-Signal Transduction,
pubmed-meshheading:11124118-Temperature,
pubmed-meshheading:11124118-Wnt1 Protein
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pubmed:year |
2001
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pubmed:articleTitle |
Hindgut visceral mesoderm requires an ectodermal template for normal development in Drosophila.
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pubmed:affiliation |
Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 2EJ, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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