Source:http://linkedlifedata.com/resource/pubmed/id/11098975
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
2000-12-11
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| pubmed:abstractText |
Intestinal ischemia-reperfusion after severe shock states is often associated with bacterial translocation and intestinal barrier dysfunction. Our previous studies showed that inducible nitric oxide synthase (iNOS) gene knockout mice were resistant to endotoxin-induced bacterial translocation and ileal mucosal damage. The goal of this study was to test whether iNOS mediates bacterial translocation after intestinal ischemia-reperfusion, using iNOS knockout mice (iNOS-/-) and their wild-type littermates (iNOS+/+).
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0090-3493
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
28
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
3692-6
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| pubmed:dateRevised |
2007-11-14
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| pubmed:meshHeading |
pubmed-meshheading:11098975-Animals,
pubmed-meshheading:11098975-Bacterial Translocation,
pubmed-meshheading:11098975-Ileum,
pubmed-meshheading:11098975-Intestinal Mucosa,
pubmed-meshheading:11098975-Intestines,
pubmed-meshheading:11098975-Mesenteric Artery, Superior,
pubmed-meshheading:11098975-Mesenteric Vascular Occlusion,
pubmed-meshheading:11098975-Mice,
pubmed-meshheading:11098975-Mice, Knockout,
pubmed-meshheading:11098975-Nitric Oxide Synthase,
pubmed-meshheading:11098975-Prospective Studies,
pubmed-meshheading:11098975-Regional Blood Flow,
pubmed-meshheading:11098975-Reperfusion Injury,
pubmed-meshheading:11098975-Shock, Septic
|
| pubmed:year |
2000
|
| pubmed:articleTitle |
Inducible nitric oxide synthase gene knockout mice have increased resistance to gut injury and bacterial translocation after an intestinal ischemia-reperfusion injury.
|
| pubmed:affiliation |
Department of Surgery, New Jersey Medical School, UMDNJ, Newark 07103-2714, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|