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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
2000-12-12
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pubmed:abstractText |
Adhesion and migration of retinal pigment epithelial (RPE) cells to provisional extracellular matrices (ECM) is important in the development of epiretinal membranes found in proliferative vitreoretinopathy (PVR). Tumor necrosis factor alpha (TNF-alpha) is found in PVR membranes and regulates many functions of RPE cells. In this study, the effects of TNF-alpha on adhesion and migration of RPE cells to various components of ECM were examined and elucidation of the mechanism of the response was attempted.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Calmodulin-Dependent...,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Fibronectins,
http://linkedlifedata.com/resource/pubmed/chemical/Flavonoids,
http://linkedlifedata.com/resource/pubmed/chemical/Integrins,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase...,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/PD 98059,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Collagen,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fibronectin,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4324-32
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:11095634-Calcium-Calmodulin-Dependent Protein Kinases,
pubmed-meshheading:11095634-Cell Adhesion,
pubmed-meshheading:11095634-Cell Movement,
pubmed-meshheading:11095634-Collagen,
pubmed-meshheading:11095634-DNA Primers,
pubmed-meshheading:11095634-Drug Combinations,
pubmed-meshheading:11095634-Enzyme Inhibitors,
pubmed-meshheading:11095634-Extracellular Matrix,
pubmed-meshheading:11095634-Fibronectins,
pubmed-meshheading:11095634-Flavonoids,
pubmed-meshheading:11095634-Humans,
pubmed-meshheading:11095634-Immunoblotting,
pubmed-meshheading:11095634-Integrins,
pubmed-meshheading:11095634-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:11095634-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:11095634-Mitogen-Activated Protein Kinase Kinases,
pubmed-meshheading:11095634-Mitogen-Activated Protein Kinases,
pubmed-meshheading:11095634-Pigment Epithelium of Eye,
pubmed-meshheading:11095634-Receptors, Collagen,
pubmed-meshheading:11095634-Receptors, Fibronectin,
pubmed-meshheading:11095634-Tumor Necrosis Factor-alpha
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pubmed:year |
2000
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pubmed:articleTitle |
Promotion of adhesion and migration of RPE cells to provisional extracellular matrices by TNF-alpha.
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pubmed:affiliation |
Departments of Pathology and. Ophthalmology, Keck School of Medicine at the University of Southern California, Los Angeles, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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