11088029

Source:http://linkedlifedata.com/resource/pubmed/id/11088029

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0022116, umls-concept:C0024128, umls-concept:C0035126, umls-concept:C1517004
pubmed:issue	6
pubmed:dateCreated	2000-12-20
pubmed:abstractText	The nonspecific immune response with activation of the complement system and polymorphonuclear leukocytes is important for the mediation of reperfusion injury after lung transplantation. In this study, we investigated the combined blockade of the complement system and leukocyte adhesion by a novel drug combining soluble complement receptor type 1 (sCR1, CD35) with the selectin ligand sialyl Lewis X (sLe(X), CD15s) synthesized to sCR1sLe(X). Both sCR1 and sCR1sLe(X) were supplied by AVANT Immunotherapeutics, Inc, Needham, Massachusetts.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0376343
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Complement Inactivator Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Complement, http://linkedlifedata.com/resource/pubmed/chemical/Thiobarbituric Acid Reactive..., http://linkedlifedata.com/resource/pubmed/chemical/soluble complement inhibitor 1
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	0022-5223
pubmed:author	pubmed-author:HamacherJJ, pubmed-author:HillingerSS, pubmed-author:SchaafJ CJC, pubmed-author:StammbergerUU
pubmed:issnType	Print
pubmed:volume	120
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1078-84
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:11088029-Animals, pubmed-meshheading:11088029-Complement Activation, pubmed-meshheading:11088029-Complement Inactivator Proteins, pubmed-meshheading:11088029-Disease Models, Animal, pubmed-meshheading:11088029-Dose-Response Relationship, Drug, pubmed-meshheading:11088029-Drug Evaluation, Preclinical, pubmed-meshheading:11088029-Leukocytes, pubmed-meshheading:11088029-Lipid Peroxidation, pubmed-meshheading:11088029-Lung Transplantation, pubmed-meshheading:11088029-Male, pubmed-meshheading:11088029-Mice, pubmed-meshheading:11088029-Neutrophils, pubmed-meshheading:11088029-Rats, pubmed-meshheading:11088029-Rats, Inbred F344, pubmed-meshheading:11088029-Receptors, Complement, pubmed-meshheading:11088029-Reperfusion Injury, pubmed-meshheading:11088029-Thiobarbituric Acid Reactive Substances, pubmed-meshheading:11088029-Time Factors, pubmed-meshheading:11088029-Transplantation, Homologous
pubmed:year	2000
pubmed:articleTitle	sCR1sLe ameliorates ischemia/reperfusion injury in experimental lung transplantation.
pubmed:affiliation	Division of General Thoracic Surgery, University Hospital, Berne, Switzerland.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, Non-U.S. Gov't