Source:http://linkedlifedata.com/resource/pubmed/id/11018266
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-11-17
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pubmed:databankReference | |
pubmed:abstractText |
The rat homologue of the human M(r) 110000 antigen, which cross-reacts with anti-carcinoembryonic antigen antibodies, was isolated from a rat lung cDNA library. The deduced amino acid sequence revealed a signal peptide, cysteine-rich and immunoglobulin-like region, serine-threonine region, and N-glycosylation sites in the extracellular portion. Northern blot analysis demonstrated a wide distribution of the mRNA in adult rat tissues and A10 rat vascular smooth muscle cells. Therefore, the rat homologue of the human M(r) 110000 antigen may be a receptor or a cell adhesion molecule rather than a specific carcinogenic antigen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
1493
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
378-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11018266-Amino Acid Sequence,
pubmed-meshheading:11018266-Animals,
pubmed-meshheading:11018266-Base Sequence,
pubmed-meshheading:11018266-Blotting, Northern,
pubmed-meshheading:11018266-Carcinoembryonic Antigen,
pubmed-meshheading:11018266-Cell Line,
pubmed-meshheading:11018266-Cells, Cultured,
pubmed-meshheading:11018266-Gene Library,
pubmed-meshheading:11018266-Humans,
pubmed-meshheading:11018266-Lung,
pubmed-meshheading:11018266-Molecular Sequence Data,
pubmed-meshheading:11018266-Muscle, Smooth, Vascular,
pubmed-meshheading:11018266-RNA, Messenger,
pubmed-meshheading:11018266-Rats,
pubmed-meshheading:11018266-Rats, Sprague-Dawley,
pubmed-meshheading:11018266-Sequence Homology, Amino Acid
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pubmed:year |
2000
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pubmed:articleTitle |
Rat homologue of the human M(r) 110000 antigen is the protein that expresses widely in various tissues.
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pubmed:affiliation |
Department of Pharmacology, Shinshu University School of Medicine, Asahi 3-1-1, 390-8621, Matsumoto, Japan. nakane@sch.md.shinshu-u.ac.jp
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pubmed:publicationType |
Journal Article,
Comparative Study
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