|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0009758,
umls-concept:C0016030,
umls-concept:C0021753,
umls-concept:C0086418,
umls-concept:C0162745,
umls-concept:C0164371,
umls-concept:C0165519,
umls-concept:C0851285,
umls-concept:C0878693,
umls-concept:C1456820,
umls-concept:C1522483
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|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2000-9-14
|
|
pubmed:abstractText |
Overexpression and increased activities of matrix metalloproteinases (MMPs) have recently been reported in cultured conjunctival fibroblasts from patients with conjunctivochalasis. The role of inflammatory cytokines in modulating expression of MMPs, their tissue inhibitors (TIMPs), and urokinase plasminogen activator (uPA) as potential contributors to the pathogenesis of conjunctivochalasis was investigated.
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pubmed:grant |
|
|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0146-0404
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
41
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2922-9
|
|
pubmed:dateRevised |
2008-11-21
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|
pubmed:meshHeading |
pubmed-meshheading:10967046-Blotting, Northern,
pubmed-meshheading:10967046-Blotting, Western,
pubmed-meshheading:10967046-Cells, Cultured,
pubmed-meshheading:10967046-Collagenases,
pubmed-meshheading:10967046-Conjunctiva,
pubmed-meshheading:10967046-Conjunctival Diseases,
pubmed-meshheading:10967046-DNA Probes,
pubmed-meshheading:10967046-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10967046-Fibroblasts,
pubmed-meshheading:10967046-Humans,
pubmed-meshheading:10967046-Interleukin-1,
pubmed-meshheading:10967046-Matrix Metalloproteinase 3,
pubmed-meshheading:10967046-Matrix Metalloproteinase 9,
pubmed-meshheading:10967046-RNA,
pubmed-meshheading:10967046-RNA, Messenger,
pubmed-meshheading:10967046-Tumor Necrosis Factor-alpha,
pubmed-meshheading:10967046-Up-Regulation,
pubmed-meshheading:10967046-Urokinase-Type Plasminogen Activator
|
|
pubmed:year |
2000
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|
pubmed:articleTitle |
Regulation of collagenase, stromelysin, and gelatinase B in human conjunctival and conjunctivochalasis fibroblasts by interleukin-1beta and tumor necrosis factor-alpha.
|
|
pubmed:affiliation |
Ocular Surface and Tear Center, Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 33136, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
