rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2000-8-10
|
pubmed:abstractText |
The potential of murine monoclonal anti-IgE antibodies as long-term therapy for atopic diseases will have to rely, for the time being, on passive antibody administration. There is therefore considerable interest in developing a peptide-based vaccine for active immunization to elicit long-term protective anti-IgE antibodies in the patient. It has been shown that some human IgG autoanti-IgE antibodies have the ability to partially block the binding of IgE to Fc receptors such as Fc epsilonRI. Therefore, the epitopes recognized by such antibodies could have vaccine potential.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0954-7894
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1041-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10848928-Amino Acid Motifs,
pubmed-meshheading:10848928-Asthma,
pubmed-meshheading:10848928-Autoantibodies,
pubmed-meshheading:10848928-Bacteriophages,
pubmed-meshheading:10848928-Chromatography, Affinity,
pubmed-meshheading:10848928-DNA Primers,
pubmed-meshheading:10848928-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10848928-Epitopes,
pubmed-meshheading:10848928-Humans,
pubmed-meshheading:10848928-Immunoglobulin E,
pubmed-meshheading:10848928-Immunoglobulin G,
pubmed-meshheading:10848928-Peptide Fragments,
pubmed-meshheading:10848928-Peptide Library,
pubmed-meshheading:10848928-Polymerase Chain Reaction
|
pubmed:year |
2000
|
pubmed:articleTitle |
Identification of peptide motifs recognized by a human IgG autoanti-IgE antibody using a phage display library.
|
pubmed:affiliation |
Division of Molecular and Clinical Immunology, University of Nottingham, Faculty of Medicine & Health Sciences, Nottingham, NG7 2UH, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|