Linked Life Data

10822261

Source:http://linkedlifedata.com/resource/pubmed/id/10822261

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-7-27
pubmed:abstractText
Drosophila oogenesis involves the coordinated development of germ cells and an overlying follicular epithelium. The follicle cells provide a genetically tractable system to investigate the cell biology of patterning and morphogenesis. Follicle cells initially form a cuboidal epithelium surrounding a syncytium of nurse cells and oocyte. Epithelial structure is maintained as these cells reorganize to create the three dimensional architecture of the eggshell. Both long-range and short-range cell-cell communications pattern the domains of follicle cells that will create specific eggshell structures. After terminal differentiation to deposit the eggshell proteins, the follicle cells die. This review summarizes recent progress in understanding the cell-cell communication that orchestrates follicle cell patterning and migrations. DE-cadherin-mediated adhesion is important at several steps in egg chamber formation and follicle cell migration. Notch signaling is critical during each successive round of patterning and migration. Integration of bone morphogenetic protein (BMP) and epidermal growth factor (EGF) signals patterns the elaborate structures of the dorsal-anterior eggshell.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1058-8388
pubmed:author
pubmed:issnType
Print
pubmed:volume
218
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
80-93
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells.
pubmed:affiliation
Cutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown 02129, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't