Linked Life Data

10802537

Source:http://linkedlifedata.com/resource/pubmed/id/10802537

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-7-21
pubmed:abstractText
Mammalian homologues of Staufen, a protein involved in localizing mRNAs during oogenesis and early central nervous system development in Drosophila, have been identified recently. The mammalian staufen gene encodes a protein containing several conserved double-stranded mRNA-binding domains and is expressed in hippocampal neurons. The mammalian Staufen protein forms granules that are transported to the distal dendrite during neuronal maturation. The Staufen granules colocalize with ribonuclear particles that transport mRNA to the dendrites. These findings might provide clues to a mechanism of mRNA transport conserved in mammalian neurons and Drosophila oogenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0962-8924
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
220-4
pubmed:dateRevised
2008-10-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Staufen: a common component of mRNA transport in oocytes and neurons?
pubmed:affiliation
Howard Hughes Medical Institute, Dept of Physiology and Biochemistry, University of California, San Francisco 94143-0725, USA.
pubmed:publicationType
Journal Article, Review