|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0026473,
umls-concept:C0033268,
umls-concept:C0035820,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0231441,
umls-concept:C0332307,
umls-concept:C0597357,
umls-concept:C1456820,
umls-concept:C1554080,
umls-concept:C1706198
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|
pubmed:issue |
3
|
|
pubmed:dateCreated |
2000-4-7
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|
pubmed:abstractText |
Small IgG rheumatoid factor immune complexes may provide the trigger for macrophage-derived tumor necrosis factor alpha (TNFalpha) production in rheumatoid arthritis. Immune complexes may bind to any of 3 IgG Fc receptors (FcgammaR). Therefore, the ability of monocyte-derived macrophages to produce TNFalpha was examined following ligation of each of the 3 human FcgammaR, using murine monoclonal antibodies (mAb) to each receptor as a model for small immune complexes.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
43
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
608-16
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:10728755-Antibodies, Monoclonal,
pubmed-meshheading:10728755-Arthritis, Rheumatoid,
pubmed-meshheading:10728755-Cell Adhesion,
pubmed-meshheading:10728755-Humans,
pubmed-meshheading:10728755-Immunoglobulin Fab Fragments,
pubmed-meshheading:10728755-Monocytes,
pubmed-meshheading:10728755-Receptors, IgG,
pubmed-meshheading:10728755-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Induction of tumor necrosis factor alpha production by adhered human monocytes: a key role for Fcgamma receptor type IIIa in rheumatoid arthritis.
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|
pubmed:affiliation |
University College London, UK.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
