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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2000-4-27
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pubmed:abstractText |
There is a clear and growing need for data regarding BRCA1 and BRCA2 mutation frequencies among breast carcinoma cases not specifically ascertained on the basis of extreme family history profiles. Toward this end, the authors previously reported results with regard to BRCA1 in breast carcinoma patients drawn from a population-based study. In the current study the authors present new findings concerning BRCA2 mutation frequency in this same population, as well as summary data regarding the combined contribution of these two genes.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2000 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1393-402
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10717622-Adult,
pubmed-meshheading:10717622-Age Factors,
pubmed-meshheading:10717622-BRCA2 Protein,
pubmed-meshheading:10717622-Breast Neoplasms,
pubmed-meshheading:10717622-Carcinoma,
pubmed-meshheading:10717622-Case-Control Studies,
pubmed-meshheading:10717622-Codon,
pubmed-meshheading:10717622-Confidence Intervals,
pubmed-meshheading:10717622-Female,
pubmed-meshheading:10717622-Frameshift Mutation,
pubmed-meshheading:10717622-Genes, BRCA1,
pubmed-meshheading:10717622-Genetic Markers,
pubmed-meshheading:10717622-Genetic Predisposition to Disease,
pubmed-meshheading:10717622-Germ-Line Mutation,
pubmed-meshheading:10717622-Heterozygote,
pubmed-meshheading:10717622-Humans,
pubmed-meshheading:10717622-Middle Aged,
pubmed-meshheading:10717622-Mutation, Missense,
pubmed-meshheading:10717622-Neoplasm Proteins,
pubmed-meshheading:10717622-Ovarian Neoplasms,
pubmed-meshheading:10717622-Polymorphism, Genetic,
pubmed-meshheading:10717622-Population Surveillance,
pubmed-meshheading:10717622-Risk Factors,
pubmed-meshheading:10717622-Transcription Factors
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pubmed:year |
2000
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pubmed:articleTitle |
Frequency of BRCA1/BRCA2 mutations in a population-based sample of young breast carcinoma cases.
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pubmed:affiliation |
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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