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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
24
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pubmed:dateCreated |
2000-2-3
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pubmed:abstractText |
A new cathepsin B inhibitor, tokaramide A (1) has been isolated from the marine sponge Theonella aff. mirabilis. Its structure was determined by spectroscopic and chemical methods. Tokaramide A inhibits cathepsin B with an IC50 value of 29.0 ng/mL.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3397-402
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10617079-Animals,
pubmed-meshheading:10617079-Cathepsin B,
pubmed-meshheading:10617079-Chromatography, High Pressure Liquid,
pubmed-meshheading:10617079-Cysteine Proteinase Inhibitors,
pubmed-meshheading:10617079-Magnetic Resonance Spectroscopy,
pubmed-meshheading:10617079-Oligopeptides,
pubmed-meshheading:10617079-Porifera,
pubmed-meshheading:10617079-Spectrometry, Mass, Fast Atom Bombardment,
pubmed-meshheading:10617079-Stereoisomerism
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pubmed:year |
1999
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pubmed:articleTitle |
Tokaramide A, a new cathepsin B inhibitor from the marine sponge Theonella aff. mirabilis.
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pubmed:affiliation |
Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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